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Important Safety Information for Saxenda ® liraglutide injection 3 mg WARNING: RISK OF THYROID C-CELL TUMORS Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice.

Important Safety Information for Wegovy ® WARNING: RISK OF THYROID C-CELL TUMORS In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures.

It is unknown whether Wegovy ® causes thyroid C-cell tumors, including medullary thyroid carcinoma MTC , in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined Wegovy ® is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 MEN 2.

Counsel patients regarding the potential risk for MTC with the use of Wegovy ® and inform them of symptoms of thyroid tumors e.

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Counsel patients regarding the potential risk of MTC with use of Saxenda ® and inform them of symptoms of thyroid tumors eg, a mass in the neck, dysphagia, dyspnea, persistent hoarseness. Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Saxenda ®.

Saxenda ® liraglutide injection 3 mg is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in:.

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